Please confirm that an ethics committee approval has been applied for or granted: Yes: I’m uploading the Ethics Committee Approval as a PDF file with this abstract submission

Background and Aims Surgical replacement of the knee joint can result in severe postoperative pain affecting functional outcomes in the long run.

Methods Following institutional ethics board approval for this multi-arm double blinded RCT,patients recruited after obtaining informed consent.They were randomised into one of four groups and provided with a combination of USG & nerve stimulator guided interventions. Group A consisted of a conventional adductor canal catheter placement.Group B,C& D involved a catheter inserted in the proximal adductor canal at the level of nerve to vastus intermedius (confirmed with nerve stimulation).In addition, Group C received single nerve injections to anterior cutaneous nerves of thigh. Group D received the catheter and single injections to both anterior cutaneous nerves and descending branch of nerve to vastus lateralis. All these patients received infiltration of the posterior capsule of knee as well. Postoperative pain scores, incidences of motor block and rescue analgesia were analysed.

Results In this interim analysis we present 72 patients who were followed up 120 hours postoperatively.