Background and Aims Posterior quadratus lumborum block is accepted analgesic strategy in abdominal surgery. We examined whether bilateral, single-injection posterior quadratus lumborum block with ropivacaine could improve on postoperative analgesia compared to 0.9% saline in patients undergoing laparoscopic hepatectomy.
Methods Ninety-four patients were randomized to receive bilateral posterior quadratus lumborum block (20 mL of 0.375% ropivacaine on each side, 150 mg total) or control group (20 mL of 0.9% saline on each side). Primary outcome was cumulative opioid consumption during the first 24 h after surgery. Secondary outcomes included pain scores, intraoperative parameters and recovery parameters.
Results Mean cumulative opioid consumption during the first 24 h after surgery was 31.2 ± 22.4 mg in quadratus lumborum block group (n=46) and 34.5 ±
19.4 mg in control group (n=46, mean difference: -3.3 mg, 95% confidence interval, -12.0 to 5.4, p=0.453). Median resting pain score at 1 h post- surgery was significantly lower in quadratus lumborum block group (5 [4, 6.25] vs. 7 [4.75, 8] , p=0.035). There were no significant differences in resting or coughing pain scores at other time points and other secondary outcomes.
Conclusions Bilateral posterior quadratus lumborum block did not reduce the cumulative opioid consumption during the first 24 h after laparoscopic hepatectomy.
ethics committee approval
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