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EP112 Anterior quadratus lumborum block for analgesia after living donor renal transplantation: A double-blinded randomized controlled trial
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  1. Youngwon Kim1 and
  2. Sun-Kyung Park2
  1. 1Anesthesiology and pain medicine, Yonsei University Severance hospital, Seoul, Korea
  2. 2Anesthesiology and pain medicine, Yonsei University College of Medicine, Seoul, Korea

Abstract

Application for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)

Background and Aims Analgesic options are limited for postoperative pain after renal transplantation. This study aimed to investigate whether a unilateral anterior quadratus lumborum block would reduce postoperative opioid consumption after living donor renal transplantation in the context of multimodal analgesia.

Methods Eighty-eight adult patients undergoing living donor renal transplantation were randomly allocated to receive either unilateral anterior quadratus lumborum block (30ml ropivacaine 0.375%) or sham block (normal saline) on the operated side. All patients received multimodal analgesia including scheduled administration of acetaminophen and a fentanyl intravenous patient-controlled analgesia. Primary outcome was total opioid consumption for the first postoperative 24 hours (oral morphine milligram equivalent [MME]). Secondary outcomes included pain scores, time to first opioid, cutaneous distribution of sensory blockade, motor weakness, nausea/vomiting, quality of recovery scores, time to first ambulate, and hospital stays.

Results Total opioid consumption in the postoperative 24 hours was not significantly different between the intervention group and control group (median [IQR], 160.5 [78–249.8] vs. 187.5 [93–309] MME; median difference [95% CI], -27 [-78 to 24], P=0.285). There were no differences in secondary outcomes.

Abstract EP112 Figure 1

CONSORT flow diagram

Abstract EP112 Table 1

Patient demographics and baseline data

Abstract EP112 Table 2

Postoperative analgesic consumptions, pain scores, and complications

Conclusions Anterior quadratus lumborum block did not reduce opioid consumption after living donor renal transplantation in the setting of multimodal analgesia. These findings do not support the routine administration of the anterior quadratus lumborum in this surgical population.

  • Anterior quadratus lumborum block
  • renal transplantation
  • postoperative analgesia

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