Background and Aims To evaluate the results of ultrasound-guided interscalene block on wound healing and immunity in open shoulder surgery cases.
Methods Participants were randomized into 2 groups. Group GA: Standard ASA monitoring, 2 mg/kg propofol, 0.6mg/kg rocuronium bromide, induction with 1µcg/kg fentanyl, 2MAC sevoflurane + 40% air mixture, and maintenance with 2L/min. Before extubation, 1 mg/kg tramadol and 15 mg/kg paracetamol iv. Paracetamol was repeated at 8 hour intervals. Group IS: Standard ASA monitoring and ultrasound guided interscalene block with 20 ml of 0.25% bupivacaine. Before postoperative unit, 1 mg/kg tramadol and 15 mg/kg paracetamol iv. Paracetamol was repeated at 8 hour intervals. Platelet count, PDGF (Platelet growth factor), TGF-α (transforming growth factor), EGF (epidermal growth factor), IL-1/IL-2, TNF-α (tumor necrosis factor alpha) measurements were taken half an hour before the operation, repeated 24 and 48 hours postoperatively. The patients were called for wound evaluation on the 14th day). Demographic data, VAS scores, side effects, additional analgesic requirement, mobilization time, hospital stay were recorded and evaluated statistically. The study is ongoing and the parameters of the immunity arm will be shared
Results The platelet values at the postoperative 24th and 48th hours were significantly higher in the IS group (table 1) (p < 0.05)(figure 1).The VAS scores and the amount of additional analgesic used, side effects, mobilization time were higher in the GA (p < 0.05) (figure 2-3).
Conclusions The positive effects of interscalene block on wound healing and postoperative period were observed. Results on immunity will also be shared.
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