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EP212 Ilioinguinal Block with Liposomal Bupivacaine for Lower Extremities Revascularization: Have We Found the ‘Right’ Block?
  1. Carmelina Gurrieri1,
  2. Ghaith Almhanni2,
  3. Indrani Sen2,
  4. Jason Beckermann3,
  5. Andrew Calvin4,
  6. Thomas Carmody2 and
  7. Tiziano Tallarita2
  1. 1Anesthesiology and Perioperative Medicine, Mayo Clinic Health System, Eau Claire, USA
  2. 2Department of Cardiovascular Surgery, Mayo Clinic Health System, Eau Claire, USA
  3. 3Department of General Surgery, Mayo Clinic Health System, Eau Claire, USA
  4. 4Department of Cardiology and Vascular medicine, Mayo Clinic Health System, Eau Claire, USA


Background and Aims As part of multimodal analgesia techniques, regional anesthesia plays a crucial role in reducing opioids usage. The aim of our study was to analyze the efficacy of intraoperative ilioinguinal block with liposomal bupivacaine (IIB/LB) in reducing intra- and post-operative use of narcotics in lower extremities vascular surgeries.

Methods We reviewed the clinical data of 107 patients who underwent elective lower extremities vascular surgeries at our institution from January 2017 to December 2022. Patients were divided into two groups: Group I (n=41 [38%]) received an intraoperative IIB/LB; Group II (n=66 [62%]) did not receive regional anesthesia. Endpoints included procedural metrics, intra- and post-operative narcotic use at 12, 24, 48 and 72 hours after surgery.

Results Both groups had similar demographics and operative indications. Median dose of intraoperative opioids in IV morphine equivalents was lower for Group I versus Group II (22.5 ± 10.1 vs 28.4 ± 12.2, P=0.01). Median postoperative IV morphine equivalents were lower for Group I versus Group II (at 12h 81.5±36.1 vs 108.1±44.5, P <0.001; at 24h 88.5±45.3 vs 125.4± 54.9, P <0.001; at 48h 121.7±75.2 vs 161.8±78.6, P=0.02; at 72h

121.7±76.1 vs 199.8±109.4, P<0.001). There were no significant differences in mortality or major adverse events between the two groups.

Abstract EP212 Table 1

Opioid usage

Abstract EP212 Table 2

Surgical, anesthetic characteristics and outcome

Conclusions Ilioinguinal block with liposomal bupivacaine significantly reduced the intra- and post-operative opioids use up to 72 hours, and it should be considered as part of multimodal analgesia approach for infra-inguinal vascular surgeries.

Ethics Committee Approval

  • ilioinguinal block
  • regional anesthesia
  • vascular surgery
  • liposomal bupivacaine

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