Background and Aims Spine surgery in the thoracolumbar region is one of the most common surgeries performed.The pain management during perioperative period remains a challenge. Interfascial plane block likes erector spinae plane block and thoracolumbar interfascial plane block exerts effective analgesic effect during perioperative period in patients undergoing lumbar surgery.

Methods In this randomised, prospective double-blind study, 60 American Society of Anesthesiologists I/II patients, within the age group of 18–60 years scheduled for single or twolevel lumbar discectomy or primary lumbar laminoplasty of two or less levels were recruited. The patients were allocated in either of the two groups: group I: general anaesthesia plus modified thoracolumbar interfascial plane block (mTLIP Group) and group II: general anaesthesia plus erector spinae plane block (ESP group). Perioperative fentanyl consumption and postoperative pain score was recorded for 48 hours. Postoperative patient satisfaction andside effects like nausea, vomiting and sedation were also recorded.

Results Postoperative 48 h fentanyl consumption (µg) was also less in Group II (124.16 ± 80.83) than Group I (189.66 ± 141.11) and this difference was statistically significant (P < 0.05). The difference in postoperative pain severity score between the both the groups was significant for the most of the time periods (P< 0.05).

Conclusions US-guided ESP block provides superior postoperative analgesia than mTLIP block during first 24 h in patients undergoing spine surgeries.