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Liposomal bupivacaine versus bupivacaine hydrochloride: are we changing the outcomes?
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  1. Alaa Abd-Elsayed
  1. University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53705, USA
  1. Correspondence to Dr Alaa Abd-Elsayed, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53705, USA; alaaawny{at}hotmail.com

https://doi.org/10.1136/rapm-2021-102683

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    Abstract

    Hanns-Christian et al 1 conducted a literature review with the objective of determining whether there is a difference in postoperative pain scores and opioid consumption between patients who received liposomal bupivacaine and patients who received bupivacaine hydrochloride.

    The authors concluded that the beneficial effect on both postoperative pain scores and opioid consumption was small but not clinically relevant.1

    Figure

    Reference

    1. ↵
      2. Dinges H-C ,
      3. Wiesmann T ,
      4. Otremba B ,
      5. Hanns-Christian D , et al
      . The analgesic efficacy of liposomal bupivacaine compared with bupivacaine hydrochloride for the prevention of postoperative pain: a systematic review and meta-analysis with trial sequential analysis. Reg Anesth Pain Med 2021;46:490–8.doi:10.1136/rapm-2020-102427 pmid:http://www.ncbi.nlm.nih.gov/pubmed/33837139
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    Footnotes

    • Contributors AA-E designed and produced the infographic.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Commissioned; internally peer reviewed.

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