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- drug-related side effects and adverse reactions
- nerve block
- acute pain
As Hanson et al 1 described in their recent study, renal transplant surgery can be associated with moderate to severe pain. Transversus abdominis plane (TAP) blocks can provide effective postoperative analgesia but require expertize in regional anesthesia and can lead to some complications. In this prospective, randomized, unblinded noninferiority study of lidocaine infusion versus TAP block for renal transplant, 120 patients were assigned one of the two interventions. The primary outcome was opioid consumption during the first 24 postoperative hours. Lidocaine infusion was noninferior to unilateral, single-shot TAP block in providing postoperative analgesia after renal transplant. Patient satisfaction scores were higher for lidocaine infusion group, but two patients described local anesthetic systemic toxicity symptoms in the first 24 hours with lidocaine and two more patients reported symptoms at the 48-hour time point in the lidocaine group. The authors concluded that a lidocaine infusion may be an effective alternative to a TAP block when it is contraindicated or when the necessary skills are not available.
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We would like to acknowledge Jim Snively, artist, of Pittsburgh, PA, for creation of this infographic.
Twitter @ESchwenkMD, @dr_rajgupta
Contributors ESS designed the infographic and RKG helped edit and approved the infographic.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer-reviewed.