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Safety and Side Effect Profile of Liposome Bupivacaine (Exparel) in Peripheral Nerve Blocks

Authors

  • Brian M. Ilfeld From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  • Eugene R. Viscusi From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  • Admir Hadzic From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  • Harold S. Minkowitz From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  • Michael D. Morren From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  • Janice Lookabaugh From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  • Girish P. Joshi From the *Department of Anesthesiology, University of California, San Diego, San Diego, CA; †Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA; ‡Department of Anesthesiology, Mount Sinai St Luke’s-Roosevelt Hospital, New York, NY; §Department of Anesthesiology, Memorial Hermann Memorial City Medical Center, Houston, TX; ∥Peloton Advantage, LLC; and ¶Pacira Pharmaceuticals, Inc, Parsippany, NJ; and **Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX PubMed articlesGoogle scholar articles
  1. Address correspondence to: Brian M. Ilfeld, MD, MS, Department of Anesthesiology, University of California, San Diego, 200 W Arbor Dr, MC 8770 San Diego, CA 92103 (e-mail: bilfeld{at}ucsd.edu).

Citation

Ilfeld BM, Viscusi ER, Hadzic A, et al
Safety and Side Effect Profile of Liposome Bupivacaine (Exparel) in Peripheral Nerve Blocks
Regional Anesthesia & Pain Medicine 2015;40:572-582.

Publication history

  • First published September 1, 2015.
Online issue publication 
February 27, 2019

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Copyright © 2015 by American Society of Regional Anesthesia and Pain Medicine