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Local Anesthetic–Induced Inhibition of Human Neutrophil Priming: The Influence of Structure, Lipophilicity, and Charge

Authors

  • Susanne Picardi *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Sibylle Cartellieri *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Danja Groves *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Klaus Hahnenekamp *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Peter Gerner *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Marcel E. Durieux *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Markus F. Stevens *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands.*Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Philipp Lirk *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands.*Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  • Markus W. Hollmann *Department of Anesthesiology, University Hospital Maastricht, the Netherlands; Departments of †Anesthesiology and ‡Anesthesiology and Critical Care, University Hospital Münster, Germany; §Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Boston, MA; and ∥Department of Anesthesiology and ¶Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, the Netherlands. PubMed articlesGoogle scholar articles
  1. Address correspondence to: Philipp Lirk, MD, Department of Anesthesiology, Academic Medical Center Amsterdam, PO Box 22600, 1105 DD Amsterdam, the Netherlands (e-mail: p.lirk{at}amc.uva.nl).

Citation

Picardi S, Cartellieri S, Groves D, et al
Local Anesthetic–Induced Inhibition of Human Neutrophil Priming: The Influence of Structure, Lipophilicity, and Charge
Regional Anesthesia & Pain Medicine 2013;38:9-15.

Publication history

  • First published January 1, 2013.
Online issue publication 
February 27, 2019

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Copyright © 2013 by American Society of Regional Anesthesia and Pain Medicine