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Case Reports
Gabapentin for the Treatment and Prophylaxis of Cluster Headache
  1. Beng A. Tay, M.B.B.Ch., F.F.A.R.C.S.I., F.H.K.A.M.,
  2. Warwick D. Ngan Kee, M.B.Ch.B., M.D., F.A.N.Z.C.A., F.H.K.A.M. and
  3. David C. Chung, M.D., F.R.C.A., F.R.C.P.C., F.H.K.A.M.
  1. From the Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China.
  1. Reprint requests: Beng A. Tay, M.B.B.Ch., F.F.A.R.C.S.I., F.H.K.A.M., Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China. E-mail: taybenai{at}cuhk.edu.hk

Abstract

Background and Objectives Cluster headache is an uncommon debilitating condition for which effective management remains a challenge. We describe the use of gabapentin in the treatment and prophylaxis of cluster headache in a patient who was refractory to other treatments.

Case Report A 38-year-old man had a history of intermittent right-side headaches for 24 years, diagnosed as cluster headache. He received only partial relief from a range of conventional treatments. A trial with gabapentin 300 mg twice daily was tried and found to be effective in treatment and prophylaxis of his headaches.

Conclusion Gabapentin was effective in the treatment of a patient with cluster headache. Further investigation of gabapentin compared with conventional treatments and placebo is warranted.

  • Cluster headache
  • GABA
  • Anticonvulsants

https://doi.org/10.1053/rapm.2001.24404

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