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Current Perception Thresholds and Postoperative Pain in Schizophrenic Patients
  1. Akira Kudoh, M.D.,
  2. Hironori Ishihara, M.D. and
  3. Akitomo Matsuki, M.D.
  1. From the Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki, Japan.
  1. Reprint requests: Akira Kudoh, M.D., Department of Anesthesiology, University of Hirosaki School of Medicine, 5 Zaifucho, Hirosaki 036, Aomori, Japan.

Abstract

Background and Objectives Schizophrenic patients may have less sensitivity to pain; however, pain insensitivity in schizophrenia has not been adequately evaluated. We investigated current perception threshold (CPT) and postoperative pain intensity in patients with long-standing and treated schizophrenia and control patients.

Methods We measured CPTs for 2,000 Hz, 250 Hz, and 5 Hz and postoperative pain intensity using a visual analogue scale (VAS) in 50 chronic schizophrenic patients who were on chronic phenothiazine derivatives (> 10 years) and for 25 control patients.

Results CPTs for 2,000 Hz, 250 Hz, and 5 Hz in schizophrenic patients were 334.2 ± 112.2, 303.9 ± 117.1, and 165.0 ± 72.3, respectively. CPTs for 2,000 Hz, 250 Hz, and 5 Hz in schizophrenic patients were significantly higher than those of control patients. VAS pain scores of schizophrenic patients were 4.0 ± 1.7 at 2 hours post-operatively and 3.8 ± 1.5 at 5 hours postoperatively, which were significantly (P < .05) lower than those (5.0 ± 1.6 and 5.1 ± 1.9) of the control group.

Conclusions Chronic schizophrenic patients have increased current perception threshold and lower VAS pain scores in postoperative pain compared with control patients.

  • Schizophrenia
  • Current perception threshold
  • Postoperative pain

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