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Long-term Use of Subarachnoid Clonidine for Analgesia in Refractory Reflex Sympathetic Dystrophy
  1. Atika A. Kabeer, B.Sc., M.B., B.Ch. and
  2. Paul A. J. Hardy, B.Sc., M.D., M.A.
  1. Gloucestershire Royal Hospital, Gloucester, United Kingdom
  1. Reprint requests: Paul A.J. Hardy, Department of Anesthesiology, University of Wisconsin, Madison, B6/ 319 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792-3272.


Background and Objectives A case is presented of intractable reflex sympathetic dystrophy resistant to all other types of treatment.

Methods Twice daily subarachnoid clonidine was used to manage the symptoms via an implanted drug delivery system.

Results The patient has successfully administered his own subarachnoid clonidine for over 18 months with no signs of tolerance or toxicity.

Conclusions Continuous subarachnoid clonidine may offer a solution to the management of some cases of intractable reflex sympathetic dystrophy.

  • reflex sympathetic dystrophy
  • sympathetic-mediated pain
  • subarachnoid analgesia
  • clonidine

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