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Spinal Anesthesia With Meperidine as the Sole Agent for Cesarean Delivery
  1. Nguyen T. V. Thi*,
  2. G. Orliaguet,
  3. T. H. Ngû* and
  4. F. Bonnet
  1. *From the Service d’Anesthésie Réanimation, Hôpital Nhân Dân Gia Dïnh, Ho Chi Minh Ville, Vietnam
  2. Département d’Anesthésie Réanimation, Hôpital Henri Mondor Créteil, France
  1. Reprint requests: F. Bonnet, M.D., Réanimation Chirurgicale, Hôpital Henri Mondor, 51, avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France.


Background and Objectives Meperidine is an opioid with local anesthetic properties that produces spinal anesthesia after subarachnoid injection for surgical procedures. The aim of this study was to evaluate the clinical relevance of spinal meperidine for cesarean delivery.

Methods Twenty-eight ASA I-III parturients scheduled for cesarean delivery were included in the study. Meperidine 1 mg/kg was administered subarachnoid. Patients were monitored for appropriate anesthesia and side effects.

Results Cesarean delivery was successfully performed under spinal meperidine in 22 cases: two cases required general anesthesia before incision and the duration of sensory anesthesia was too short in four cases. Side effects included moderate hypotension (decrease in arterial blood pressure > 30 mm Hg in 36% of the cases), nausea (32%), and pruritus (10.7 %). No respiratory depression was documented in mothers and newborns.

Conclusions Although short-acting, meperidine can be used as a substitute for local anesthetics for cesarean delivery, especially when local anesthetics are not available.

  • analgesia
  • postoperative
  • analgesics
  • meperidine
  • anesthesia
  • obstetric anesthetic technique
  • spinal

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