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Comparison of Onset Time between 0.5% Bupivacaine and 3% 2-Chloroprocaine with and without 75 μg Fentanyl
  1. Calvin Johnson, M.D.*,
  2. Bernard J. Ransil, M.D.** and
  3. Nancy Oriol, M.D.
  1. From the Department of Anesthesia Beth Israel Hospital, 330 Brookline Ave., Boston, Massachusetts
  2. *Clinical Fellow in Obstetrical Anesthesia, Beth Israel Hospital, Harvard Medical School
  3. **Director, Core Laboratory, Clinical Research Center, Beth Israel Hospital, and Associate Professor of Medicine, Beth Israel Hospital, Harvard Medical School
  4. Director of Obstetric Anesthesia, Beth Israel Hospital, and Clinical Instructor Anesthesia, Harvard Medical School

Abstract

We tested the hypothesis that the addition of 75 μg fentanyl to 0.5% bupivacaine would reduce the onset time of surgical anesthesia for cesarean delivery to equal the onset time of 3% 2-chloroprocaine and would have no effect when added to 3% 2-chloroprocaine. Fentanyl was found to reduce the onset time of bupivacaine to equal the onset time of 2-chloroprocaine and have no effect when added to 2-chloroprocaine.

  • Anesthesia
  • epidural onset time
  • local anesthetics
  • bupivacaine
  • 2-chloroprocaine
  • analgesics
  • narcotics
  • fentanyl

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