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Effects of Etidocaine Administered Epidurally on Changes in Somatosensory Evoked Potentials after Dermatomal Stimulation
  1. Claus Lund, M.D.*,
  2. Torben Mogensen, M.D.*,
  3. Ole Bo Hansen, M.D.*,
  4. Susanne Qvitzau, M.D.** and
  5. Henrik Kehlet, M.D., PH.D.**
  1. *Department of Anesthesiology, Copenhagen University Medical School, Hvidovre Hospital, Hvidovre, Denmark
  2. **Department of Surgical Gastroenterology, Copenhagen University Medical School, Hvidovre Hospital, Hvidovre, Denmark


The effect of lumbar epidural anesthesia with similar volumes (approximately 20 ml) of 1% and 1.5% etidocaine on early (<0.5 seconds) somatosensory evoked potentials (SEPs) to electrical stimulation of the S1, L1 and T10 dermatomes was examined in two groups of ten patients in a randomized, double-blind study. Level of analgesia to pinprick was T7.7 ± 0.9 in the 1% group and T6.6 ± 0.6 in the 1.5% group and all patients had total motor block. Despite similar analgesia to pinprick, SEP amplitude was more reduced in the 1.5% group, in which SEPs were abolished in all patients at the L1 level.

  • Anesthetic techniques
  • epidural etidocaine
  • brain evoked potentials

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