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Choice of Local Anesthetic Affects Post-Cesarean Epidural Fentanyl Analgesia
  1. A.M. Malinow, MD*,
  2. B.L.K. Mokriski, MD,
  3. M.L. Wakefield, MD,
  4. W.J. McGuinn, MD,
  5. D.G. Martz, MD,
  6. J.N. Desverreaux, MD and
  7. M.J. Matjasko, MD§
  1. From the Department of Anesthesiology, University of Maryland School of Medicine and Hospital, University of Maryland Medical System
  2. *Assistant Professor of Anesthesiology, Obstetrics and Gynecology.
  3. Assistant Professor.
  4. Fellow in Obstetric Anesthesia.
  5. §Acting Chairperson, Associate Professor.


This prospective, randomized study compared the analgesia obtained after the epidural injection of fentanyl (50 μg) after 0.5% bupivacaine, 2% lidocaine with epinephrine 1:200,000, or 3% 2-chloroprocaine anesthesia for cesarean section. Satisfactory analgesia was obtained for up to 45 minutes mean duration after the loss of sensory anesthesia after bupivacaine and lidocaine. Analgesia following 2-chloroprocaine anesthesia did not extend beyond the regression of sensory anesthesia to pinprick. Alkalinization of the 2-chloroprocaine to a pH of 7.09 did not lengthen the duration of analgesia.

  • Analgesia
  • Post operative
  • anesthesia
  • Obstetric
  • anesthetics
  • Local narcotics
  • Fentanyl

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