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Euglycemic Hydration with Dextrose 1% in Lactated Ringer's Solution During Epidural Anesthesia for Cesarean Section
  1. Alfred T. C. Peng, MD*,
  2. Haider H. Shamsi, MD,
  3. Louis S. Blancato, MD*,
  4. Steven M. Shulman, MD*,
  5. Frank A. Chervenak, MD and
  6. Jose L. Castro, MD*
  1. *From the Departments of Anesthesiology and Obstetrics and Gynecology, St. Luke's-Roosevelt Hospital Center, Columbia University, New York, New York


This study examined the effects of three intravenous glucose (glu) concentrations administered to precesarean patients on neonatal umbilical glucose levels. Thirty patients undergoing elective cesarean section were randomly assigned to one of three groups. The three groups, each with ten patients, received one of the following intravenous solutions: (1) Ringer's lactate (RL) 1000 ml, (2) dextrose 1% in Ringer's lactate (D1RL) 1000 ml, and (3) dextrose 5% in Ringer's lactate (D5RL) 1000 ml. Umbilical artery (UA) glucose levels of groups A, B, and C were 46.8 ± 13.8 mg/dl, 79.1 ± 19.0 mg/dl, and 207.1 ± 45.9 mg/dl, respectively. Two neonates in the D5RL group, in which UA glucose was very high, later developed hypoglycemic seizures. RL yielded UA glucose levels that were hypoglycemic. In contrast, D1RL infusion resulted in euglycemic levels. In conclusion, D1RL was the solution most likely to maintain euglycemia both in mothers and neonates.

  • Euglycemia
  • Hyperglycemia
  • Hypoglycemia
  • Glucose
  • Ringer's lactate

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