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Transarterial Brachial Plexus Blockade Using High Doses of 1.5% Mepivacaine
  1. E. Cockings, MD, FRCPC*,
  2. P. L. Moore, MD and
  3. R. C. LEWIS, MD
  1. From the Department of Anesthesiology, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, Texas
  2. *Professor, Department of Anesthesiology.
  3. Staff Anesthesiologist, St. Mary's Hospital, Lubbock, Texas.
  4. Professor, Department of Orthopedic Surgery.


A transarterial technique of axillary brachial plexus block was performed using a standard dose of 50 ml of 1.5% mepivacaine on 100 patients undergoing surgery of the upper extremity. Time to onset and percent success of sensory and motor blockade were measured, as was duration of analgesia. Success rate was 99%, with only one patient requiring general anesthesia. Duration of analgesia was 3.8 ± 0.1 hours. Peak venous plasma levels of mepivacaine measured in ten patients were below those associated with systemic toxicity, and no signs of clinical toxicity were observed in any patients.

  • Transarterial
  • Axillary block
  • Brachial plexus block
  • Mepivacaine

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